Arousal Cream
$159.00 $265.00
✓ A topical prescription designed to support genital blood flow, sensitivity and physical arousal response—right where it’s applied.
Arousal Cream is a compounded topical treatment for women that combines five active ingredients: aminophylline, ergoloid mesylate, pentoxifylline, sildenafil citrate and L-arginine.
Unlike an oral medication, the cream is applied directly to the external genital area before sexual activity, providing a localized approach to female sexual arousal.
When Your Mind Is Interested, But Your Body Isn't Responding the Same Way
Female sexual arousal isn't only about desire.
Physical arousal involves increased genital blood flow, sensitivity and changes in genital tissues. For some women, the desire for sex may still be there while the physical response feels slower, weaker or simply different than it once did.
Arousal Cream is designed to focus on that physical side of sexual response.
How Arousal Cream Works
The ingredients in Arousal Cream have different pharmacologic actions, with much of the formulation centered around supporting localized circulation and nitric-oxide pathways involved in genital blood flow.
Sildenafil — Local Blood Flow Support
Sildenafil is a PDE5 inhibitor best known for its role in erectile function in men, but PDE5 and nitric-oxide signaling also play roles in female genital blood flow.
Topical sildenafil has been specifically studied in women with female sexual arousal disorder, including research examining its potential effects on physical arousal sensations.
L-Arginine — Nitric Oxide Support
L-arginine is an amino acid the body uses to produce nitric oxide.
Nitric oxide helps blood vessels relax and plays an important role in blood flow. Within female sexual physiology, this pathway is involved in genital vascular response and engorgement.
Pentoxifylline — Microcirculation
Pentoxifylline affects blood flow and microcirculation by improving red blood cell flexibility and reducing blood viscosity.
Its inclusion provides another mechanism focused on circulation within the compounded formulation.
Aminophylline & Ergoloid Mesylate
Aminophylline and ergoloid mesylate have pharmacologic effects involving vascular and smooth-muscle activity.
Together with sildenafil, L-arginine and pentoxifylline, they contribute to the multi-ingredient approach of the formulation.
Why Use a Topical Treatment?
Arousal Cream is applied directly to the external genital area rather than taken as an oral sexual-wellness medication.
That makes it an interesting option for women interested in a localized treatment focused on the physical arousal response.
The goal isn't to manufacture desire. It's to support the body's physical response when sexual interest is already there.
When to Use Arousal Cream
Arousal Cream is generally applied 15–30 minutes before sexual activity.
Simple to use: apply one pump to the clitoral area before intercourse, as directed by your provider.
Each bottle provides approximately 60 applications, making it a convenient as-needed treatment that can last quite a while depending on how frequently you use it.
Your Care Journey
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Submit Your Intake – Share your health history, symptoms and treatment goals through our secure online platform.
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Provider Consultation – A licensed provider determines whether Arousal Cream is appropriate for you.
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Prescription Approval – If approved, your prescription is coordinated with a licensed compounding pharmacy.
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Treatment Delivered – Medication is shipped directly to your door.
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Continued Care – Providers remain available for questions and follow-up.
Side Effects
Possible local side effects may include warmth, redness, itching, irritation or mild burning at the application site.
Because the ingredients can also be absorbed systemically, other side effects are possible, including headache, flushing, dizziness, nasal congestion or changes in blood pressure.
Do not apply to broken or irritated skin. Tell your provider about all medications you take, particularly nitrates, blood-pressure medications, blood thinners and other medications that may interact with the ingredients in the formulation.
What We Do / Don’t Do
We Do: Provide telemedicine consultations, connect patients with licensed medical providers, coordinate prescriptions with licensed compounding pharmacies and provide continued treatment support.
We Don’t: Manufacture or dispense medications or guarantee that a prescription will be issued.
Important
Arousal Cream is a compounded prescription medication containing aminophylline, ergoloid mesylate, pentoxifylline, sildenafil citrate and L-arginine.
This compounded formulation has not been approved by the FDA or evaluated by the FDA for safety, effectiveness or quality. Individual results may vary.
Invyncible is a telemedicine provider network, not a pharmacy. Prescriptions are filled by licensed pharmacies.
Research & References
Johnson I, et al. Preliminary Efficacy of Topical Sildenafil Cream for the Treatment of Female Sexual Arousal Disorder: A Randomized Controlled Trial. Obstetrics & Gynecology. 2024;144(2):144–152.
Thurman AR, et al. Safety of Topical Sildenafil Cream, 3.6% in a Randomized, Placebo-Controlled Trial for the Treatment of Female Sexual Arousal Disorder. Journal of Sexual Medicine. 2024;21(9):793–799.
Research Context
Research discussed above includes studies of individual ingredients and formulations that differ from the compounded Arousal Cream offered through Invyncible. The studies should not be interpreted as clinical evidence that this specific compounded combination will produce the same outcomes. Individual results may vary.
Frequently Asked Questions about Arousal Cream
1. What does Arousal Cream actually do?
Arousal Cream is a topical prescription applied directly to the external genital area. Its ingredients are intended to support pathways involved in local blood flow and the physical arousal response.
Think of it as focusing more on how your body physically responds rather than trying to create sexual desire.
2. What does Arousal Cream feel like when it starts working?
Experiences can vary. Because the formulation is applied locally and contains ingredients associated with circulation and vascular response, some women may notice sensations such as warmth or increased awareness in the area where it's applied.
It shouldn't cause significant burning or irritation. If that occurs, stop using it and contact your provider.
3. Will Arousal Cream make me want sex more?
Not necessarily—and there is an important difference between desire and physical arousal.
You can mentally want sex while your body doesn't respond as strongly as it once did. Arousal Cream is focused primarily on the physical side of sexual response rather than creating sexual desire.
4. Could Arousal Cream increase sensitivity?
Potentially. Genital sensitivity and physical arousal are influenced in part by blood flow and vascular response, which are areas targeted by ingredients in the formulation.
Research into topical sildenafil in women has also examined changes in genital arousal sensations. Individual response can vary.
5. Can Arousal Cream make orgasms feel stronger?
It's possible that changes in physical arousal or genital sensation could influence the sexual experience, but Arousal Cream hasn't been clinically established as an orgasm-enhancement treatment.
If stronger or easier-to-reach orgasms are your primary concern, tell your provider. That helps them understand what you're actually trying to improve rather than treating every sexual concern as the same problem.
6. Where do I apply Arousal Cream?
Arousal Cream is applied directly to the external genital area. Your prescription instructions specify applying one pump to the clitoral area before intercourse.
Use only as directed by your provider.
7. How quickly does Arousal Cream work?
Arousal Cream is generally applied 15–30 minutes before sexual activity.
Follow the specific timing and application instructions provided with your prescription.
8. Is Arousal Cream basically “Viagra for women”?
Not exactly.
Arousal Cream does contain sildenafil—the same active ingredient found in Viagra®—but female sexual function is more complex than simply translating a men's ED medication to women.
The cream is a compounded topical formulation containing sildenafil along with L-arginine, pentoxifylline, aminophylline and ergoloid mesylate. Its localized formulation and combination of ingredients make it very different from taking an oral sildenafil tablet.
9. How much Arousal Cream do I use, and how many applications are in one bottle?
Arousal Cream is simple to use: apply one pump to the clitoral area before intercourse, as directed by your provider.
Each bottle provides approximately 60 applications, making it an as-needed treatment that can last quite a while depending on how frequently you use it.
10. How long do the effects of Arousal Cream last?
The duration of the physical response can vary from woman to woman. Arousal Cream is intended for use around sexual activity rather than as an all-day treatment.
Follow your prescribed dosing instructions and don't reapply more frequently than directed.
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